Genome-wide analysis in over 1 million individuals of European ancestry yields improved polygenic risk scores for blood pressure traits

- Keaton, Jacob M., Kamali, Zoha, Young, William J., Lehtimäki, T, Raitakari, OT, Johnson, AD, Newton-Cheh, C, Brown, MJ, Dominiczak, AF, Sever, PJ, Poulter, N, Chambers, JC, Elosua, R, Traylor, Matthew, Siscovick, D, Esko, T, Metspalu, A, Strawbridge, RJ, Laakso, M, Hamsten, A, Hottenga, J-J, de Geus, E, Morris, AD, Palmer, CNA, Giri, Ayush, Nolte, IM, Milaneschi, Y, Marten, J, Wright, A, Zeggini, E, Howson, JMM, O'Donnell, CJ, Spector, T, Nalls, MA, Simonsick, EM, Zheng, Zhili, Liu, Y, van Duijn, CM, Butterworth, AS, Danesh, JN, Menni, C, Wareham, NJ, Khaw, K-T, Sun, YV, Wilson, PWF, Cho, K, Zeng, Jian, Visscher, PM, Denny, JC, Million Veteran Program,, Lifelines Cohort Study,, CHARGE consortium,, ICBP Consortium,, Levy, D, Edwards, TL, Munroe, PB, Snieder, H, Chasman, Daniel I., Warren, HR, Morris, Andrew P., Caulfield, Mark J., Hwang, Shih-Jen, Kooner, Jaspal S., Xie, Tian, Attia, John R., Attia, JR, Morrison, AC, Loos, RJF, Kristiansson, K, Schmidt, R, Hicks, AA, Pramstaller, PP, Nelson, CP, Samani, NJ, Vaez, Ahmad, Risch, L, Gyllensten, U, Melander, O, Riese, H, Wilson, JF, Campbell, H, Rich, SS, Psaty, BM, Lu, Y, Rotter, JI, Williams, Ariel, Guo, X, Rice, KM, Vollenweider, P, Sundström, J, Langenberg, C, Tobin, MD, Giedraitis, V, Luan, J, Tuomilehto, J, Kutalik, Z, Goleva, Slavina B., Ripatti, S, Salomaa, V, Girotto, G, Trompet, S, Jukema, JW, van der Harst, P, Ridker, PM, Giulianini, F, Vitart, V, Goel, A, Ani, Alireza, Watkins, H, Harris, SE, Deary, IJ, van der Most, PJ, Oldehinkel, AJ, Keavney, BD, Hayward, C, Campbell, A, Boehnke, M, Scott, LJ, Evangelou, Evangelos, Boutin, T, Mamasoula, C, Järvelin, M-R, Peters, A, Gieger, C, Lakatta, EG, Cucca, F, Hui, J, Knekt, P, Enroth, S, Hellwege, Jacklyn N., De Borst, MH, Polašek, O, Concas, MP, Catamo, E, Cocca, M, Li-Gao, R, Hofer, E, Schmidt, H, Spedicati, B, Waldenberger, M, Yengo, Loic, Strachan, DP, Laan, M, Teumer, A, Dörr, M, Gudnason, V, Cook, JP, Ruggiero, D, Kolcic, I, Boerwinkle, E, Traglia, M

A Multi-Layer Functional Genomic Analysis to Understand Noncoding Genetic Variation in Lipids

- Ramdas, Shweta, Judd, Jonathan, Bhatti, Konain Fatima, Noordam, R, Mauro, P, Matteo, F, McDaid, AF, Marques-Vidal, P, Wielscher, M, Trompet, S, Sattar, N, Mollehave, LT, Munz, M, Vedantam, Sailaja, Zeng, L, Huang, J, Yang, B, Poveda, A, Kurbasic, A, Schonherr, S, Forer, L, Scholz, M, Galesloot, TE, Bradfield, JP, Winkler, Thomas W., Ruotsalainen, SE, Daw, EW, Zmuda, JM, Mitchell, JS, Fuchsberger, C, Christensen, H, Brody, JA, Le, P, Feitosa, MF, Wojczynski, MK, Locke, Adam E., Hemerich, D, Preuss, M, Mangino, M, Christofidou, P, Verweij, N, Benjamins, JW, Engmann, J, Noah, TL, Verma, A, Slieker, RC, Marouli, Eirini, Lo, KS, Zilhao, NR, Kleber, ME, Delgado, GE, Huo, S, Ikeda, DD, Iha, H, Yang, J, Liu, J, Demirkan, A, Zajac, Greg J. M., Leonard, HL, Marten, J, Emmel, C, Schmidt, B, Smyth, LJ, Canadas-Garre, M, Wang, C, Nakatochi, M, Wong, A, Hutri-Kahonen, N, Wu, Kuan-Han H., Sim, X, Xia, R, Huerta-Chagoya, A, Fernandez-Lopez, JC, Lyssenko, V, Nongmaithem, SS, Sankareswaran, A, Irvin, MR, Oldmeadow, C, Kim, H-N, Ntalla, Ioanna, Ryu, S, Timmers, PRHJ, Arbeeva, L, Dorajoo, R, Lange, LA, Prasad, G, Lores-Motta, L, Pauper, M, Long, J, Li, X, Hui, Qin, Theusch, E, Takeuchi, F, Spracklen, CN, Loukola, A, Bollepalli, S, Warner, SC, Wang, YX, Wei, WB, Nutile, T, Ruggiero, D, Klarin, Derek, Sung, YJ, Chen, S, Liu, F, Kentistou, KA, Banas, B, Morgan, A, Meidtner, K, Bielak, LF, Smith, JA, Graham, Sarah E., Hilliard, Austin T., Hebbar, P, Farmaki, A-E, Hofer, E, Lin, M, Concas, MP, Vaccargiu, S, van der Most, PJ, Pitkanen, N, Cade, BE, van der Laan, SW, Wang, Z, Chitrala, KN, Weiss, S, Bentley, AR, Doumatey, AP, Adeyemo, AA, Lee, JY, Petersen, ERB, Nielsen, AA, Choi, HS, Nethander, M, Xue, C, Freitag-Wolf, S, Southam, L, Rayner, NW, Wang, Carol A., Lin, S-Y, Wang, J-S, Couture, C, Lyytikainen, L-P, Nikus, K, Cuellar-Partida, G, Thorleifsson, G, Vestergaard, H, Hidalgo, B, Giannakopoulou, O, Cai, Q, Obura, MO, van Setten, J, He, KY, Tang, H, Terzikhan, N, Shin, JH, Helgadottir, A, Jackson, RD, Reiner, AP, Martin, LW, Chen, Z, Li, L, Kawaguchi, T, Thiery, J, Bis, JC, Launer, LJ, Li, H, Gudbjartsson, DF, Nalls, MA, Raitakari, OT, Ichihara, S, Wild, SH, Nelson, CP, Campbell, H, Jager, S, Nabika, T, Al-Mulla, F, Niinikoski, H, Holm, H, Braund, PS, Kolcic, I, Kovacs, P, Giardoglou, T, Katsuya, T, de Kleijn, D, de Borst, GJ, Kim, EK, Adams, HHH, Ikram, MA, Olafsson, I, Zhu, X, Asselbergs, FW, Kraaijeveld, AO, Beulens, JWJ, Shu, X-O, Rallidis, LS, Pedersen, O, Hansen, T, Mitchell, P, Hewitt, AW, Hwang, MY, Kahonen, M, Perusse, L, Bouchard, C, Tonjes, A, Chen, Y-DI, Pennell, CE, Mori, TA, Lieb, W, Franke, A, Ohlsson, C, Han, S, Mellstrom, D, Cho, YS, Lee, H, Yuan, J-M, Koh, W-P, Rhee, SY, Woo, J-T, Heid, IM, Stark, KJ, Zimmermann, ME, Kanoni, Stavroula, Akiyama, M, Volzke, H, Homuth, G, Evans, MK, Zonderman, AB, Polasek, O, Pasterkamp, G, Hoefer, IE, Redline, S, Pahkala, K, Oldehinkel, AJ, Sakaue, S, Snieder, H, Biino, G, Schmidt, R, Schmidt, H, Bandinelli, S, Dedoussis, G, Thanaraj, TA, Peyser, PA, Kato, N, Schulze, MB, Terao, C, Girotto, G, Boger, CA, Jung, B, Joshi, PK, Bennett, DA, De Jager, PL, Lu, X, Mamakou, V, Brown, M, Caulfield, MJ, Kanai, M, Munroe, PB, Guo, X, Ciullo, M, Jonas, JB, Samani, NJ, Kaprio, J, Pajukanta, P, Tusie-Luna, T, Aguilar-Salinas, CA, Adair, LS, Zhou, W, Bechayda, SA, de Silva, HJ, Wickremasinghe, AR, Krauss, RM, Wu, J-Y, Zheng, W, den Hollander, A, Bharadwaj, D, Correa, A, Wilson, JG, Brumpton, BM, Lind, L, Heng, C-K, Nelson, AE, Golightly, YM, Wilson, JF, Penninx, B, Kim, H-L, Attia, John, Scott, RJ, Rao, DC, Rasheed, H, Arnett, DK, Walker, M, Scott, LJ, Koistinen, HA, Chandak, GR, Mercader, JM, Villalpando, CG, Orozco, L, Fornage, M, Tai, ES, Havulinna, AS, van Dam, RM, Lehtimaki, T, Chaturvedi, N, Yokota, M, Reilly, DF, McKnight, AJ, Kee, F, Jockel, K-H, McCarthy, M, Veturi, Y, Palmer, CNA, Vitart, V, Hayward, C, Simonsick, E, van Duijn, CM, Jin, Z-B, Lu, F, Hishigaki, H, Lin, X, Marz, W, Pacheco, JA, Gudnason, V, Tardif, J-C, Lettre, G, Hart, LMT, Elders, PJM, Rader, DJ, Damrauer, SM, Kumari, M, Kivimaki, M, van der Harst, P, Wang, Yuxuan, Rosenthal, EA, Spector, TD, Loos, RJF, Province, MA, Parra, EJ, Cruz, M, Psaty, BM, Brandslund, I, Pramstaller, PP, Rotimi, CN, Christensen, K, Lingren, T, Ripatti, S, Widen, E, Hakonarson, H, Grant, SFA, Kiemeney, L, de Graaf, J, Loeffler, M, Kronenberg, F, Gu, D, Erdmann, J, Feng, Q, Schunkert, H, Franks, PW, Linneberg, A, Jukema, JW, Khera, A, Mannikko, M, Jarvelin, M-R, Kutalik, Z, Francesco, C, Mook-Kanamori, DO, Kullo, IJ, van Dijk, KW, Watkins, H, Strachan, DP, Grarup, N, Sever, P, Poulter, N, Sheu, WH-H, Rotter, J, Dantoft, TM, Karpe, F, Narita, A, Neville, MJ, Timpson, NJ, Cheng, C-Y, Wong, T-Y, Khor, CC, Sabanayagam, C, Peters, A, Gieger, C, Hattersley, AT, Takayama, J, Pedersen, NL, Magnusson, PKE, Boomsma, D, de Geus, EJC, Cupples, LA, van Meurs, JBJ, Ikram, A, Ghanbari, M, Gordon-Larsen, P, Huang, W, Martin, HC, Kim, YJ, Tabara, Y, Wareham, NJ, Langenberg, C, Zeggini, E, Tuomilehto, J, Kuusisto, J, Laakso, M, Ingelsson, E, Abecasis, G, Hunt, KA, Chambers, JC, Kooner, JS, de Vries, PS, Morrison, AC, Hazelhurst, S, Ramsay, M, North, KE, Daviglus, M, Kraft, P, Martin, NG, Trivedi, B, Whitfield, JB, Abbas, S, Saleheen, D, Walters, RG, Holmes, M, Black, C, Smith, BH, Baras, A, Justice, AE, Buring, JE, Haessler, J, Ridker, PM, Chasman, D, Kooperberg, C, Tamiya, G, Yamamoto, M, van Heel, DA, Trembath, RC, Wei, W-Q, Jarvik, GP, Namjou, B, Surakka, Ida, Giulianini, F, Hayes, MG, Ritchie, MD, Jousilahti, P, Salomaa, V, Hveem, K, Asvold, BO, Kubo, M, Kamatani, Y, Okada, Y, Murakami, Y, Bradford, Y, Kim, B-J, Thorsteinsdottir, U, Stefansson, K, Zhang, J, Chen, YE, Ho, Y-L, Lynch, JA, Tsao, PS, Chang, K-M, Cho, K, Miller, JE, O'Donnell, CJ, Gaziano, JM, Wilson, P, Mohlke, KL, Frayling, TM, Hirschhorn, JN, Kathiresan, S, Boehnke, M, Grant, S, Natarajan, P, Campbell, A, Sun, Y, Morris, AP, Deloukas, P, Peloso, G, Assimes, TL, Willer, CJ, Brown, CD, Lin, K, Millwood, IY, Rasheed, A, Hindy, G, Faul, JD, Zhao, W, Wenz, Brandon, Weir, DR, Turman, C, Huang, H, Graff, M, Choudhury, A, Sengupta, D, Mahajan, A, Brown, MR, Zhang, W, Yu, K, Clarke, Shoa L., Schmidt, EM, Pandit, A, Gustafsson, S, Yin, X, Luan, J, Zhao, J-H, Matsuda, F, Jang, H-M, Yoon, K, Medina-Gomez, C, Chesi, Alessandra, Pitsillides, A, Hottenga, JJ, Wood, AR, Ji, Y, Gao, Z, Haworth, S, Mitchell, RE, Chai, JF, Aadahl, M, Bjerregaard, AA, Wells, Andrew, Yao, J, Manichaikul, A, Lee, W-J, Hsiung, CA, Warren, HR, Ramirez, J, Bork-Jensen, J, Karhus, LL, Goel, A, Sabater-Lleal, M

Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis

- Kanoni, Stavroula, Graham, Sarah E., Locke, Adam E., Matteo, F, McDaid, AF, Marques-Vidal, P, Wielscher, M, Trompet, S, Sattar, N, Mollehave, LT, Munz, M, Zeng, L, Huang, J, Marouli, Eirini, Yang, B, Poveda, A, Kurbasic, A, Lamina, C, Forer, L, Scholz, M, Galesloot, TE, Bradfeld, JP, Ruotsalainen, SE, Daw, E, Zajac, Greg J. M., Zmuda, JM, Mitchell, JS, Fuchsberger, C, Christensen, H, Brody, JA, Vazquez-Moreno, M, Feitosa, MF, Wojczynski, MK, Wang, Z, Preuss, MH, Wu, Kuan-Han H., Mangino, M, Christofdou, P, Verweij, N, Benjamins, JW, Engmann, J, Tsao, NL, Verma, A, Slieker, RC, Lo, KS, Zilhao, NR, Ntalla, Ioanna, Le, P, Kleber, ME, Delgado, GE, Huo, S, Ikeda, DD, Iha, H, Yang, J, Liu, J, Leonard, HL, Marten, J, Hui, Qin, Frank, M, Schmidt, B, Smyth, LJ, Canadas-Garre, M, Wang, Carol A., Nakatochi, M, Wong, A, Hutri-Kahonen, N, Sim, X, Xia, R, Klarin, Derek, Huerta-Chagoya, A, Fernandez-Lopez, JC, Lyssenko, V, Nongmaithem, SS, Bayyana, S, Stringham, HM, Irvin, MR, Oldmeadow, C, Kim, H-N, Ryu, S, Hilliard, Austin T., Timmers, PRHJ, Arbeeva, L, Dorajoo, R, Lange, LA, Prasad, G, Lores-Motta, L, Pauper, M, Long, J, Li, X, Theusch, E, Wang, Zeyuan, Takeuchi, F, Spracklen, CN, Loukola, A, Bollepalli, S, Warner, SC, Wang, YX, Wei, WB, Nutile, T, Ruggiero, D, Sung, YJ, Xue, Chao, Chen, S, Liu, F, Kentistou, KA, Banas, B, Nardone, GG, Meidtner, K, Bielak, LF, Smith, JA, Hebbar, P, Wang, Yuxuan, Thorleifsson, Gudmar, Farmaki, A-E, Hofer, E, Lin, M, Concas, MP, Vaccargiu, S, van der Most, PJ, Pitkanen, N, Cade, BE, van der Laan, SW, Chitrala, KN, Helgadottir, A, Weiss, S, Bentley, AR, Doumatey, AP, Adeyemo, AA, Lee, JY, Petersen, ERB, Nielsen, AA, Choi, HS, Nethander, M, Freitag-Wolf, S, Gudbjartsson, DF, Southam, L, Rayner, NW, Wang, CA, Lin, S-Y, Wang, J-S, Couture, C, Lyytikainen, L-P, Nikus, K, Cuellar-Partida, G, Vestergaard, H, Holm, H, Hidalgo, B, Giannakopoulou, O, Cai, Q, Obura, MO, van Setten, J, Liang, J, Tang, H, Terzikhan, N, Shin, JH, Olafsson, I, Jackson, RD, Reiner, AP, Martin, LW, Chen, Z, Li, L, Kawaguchi, T, Thiery, J, Bis, JC, Launer, LJ, Li, H, Hwang, MY, Nalls, MA, Raitakari, OT, Ichihara, S, Wild, SH, Nelson, CP, Campbell, H, Jager, S, Nabika, T, Al-Mulla, F, Niinikoski, H, Han, S, Braund, PS, Kolcic, I, Kovacs, P, Giardoglou, T, Katsuya, T, de Kleijn, D, de Borst, GJ, Kim, EK, Adams, HHH, Ikram, MA, Akiyama, M, Zhu, X, Asselbergs, FW, Kraaijeveld, AO, Beulens, JWJ, Shu, X-O, Rallidis, LS, Pedersen, O, Hansen, T, Mitchell, P, Hewitt, AW, Sakaue, S, Kahonen, M, Perusse, L, Bouchard, C, Tonjes, A, Chen, Y-DI, Pennell, Craig E., Mori, TA, Lieb, W, Franke, A, Ohlsson, C, Terao, C, Mellstrom, D, Cho, YS, Lee, H, Yuan, J-M, Koh, W-P, Rhee, SY, Woo, J-T, Heid, IM, Stark, KJ, Zimmermann, ME, Surakka, Ida, Kanai, M, Volzke, H, Homuth, G, Evans, MK, Zonderman, AB, Polasek, O, Pasterkamp, G, Hoefer, IE, Redline, S, Pahkala, K, Oldehinkel, AJ, Zhou, W, Snieder, H, Biino, G, Schmidt, R, Schmidt, H, Bandinelli, S, Dedoussis, G, Thanaraj, TA, Kardia, SLR, Peyser, PA, Kato, N, Brumpton, BM, Schulze, MB, Girotto, G, Boger, CA, Jung, B, Joshi, PK, Bennett, DA, De Jager, PL, Lu, X, Mamakou, V, Brown, M, Rasheed, H, Caulfeld, MJ, Munroe, PB, Guo, X, Ciullo, M, Jonas, JB, Samani, NJ, Kaprio, J, Pajukanta, P, Tusie-Luna, T, Aguilar-Salinas, CA, Havulinna, AS, Adair, LS, Bechayda, SA, de Silva, HJ, Wickremasinghe, AR, Krauss, RM, Wu, J-Y, Zheng, W, Hollander, AI, Bharadwaj, D, Correa, A, Veturi, Y, Wilson, JG, Lind, L, Heng, C-K, Nelson, AE, Golightly, YM, Wilson, JF, Penninx, B, Kim, H-L, Attia, John, Scott, RJ, Pacheco, JA, Rao, DC, Arnett, DK, Hunt, SC, Walker, M, Koistinen, HA, Chandak, GR, Mercader, JM, Costanzo, MC, Jang, D, Burtt, NP, Rosenthal, EA, Villalpando, CG, Orozco, L, Fornage, M, Tai, E, van Dam, RM, Lehtimaki, T, Chaturvedi, N, Yokota, M, Reilly, DF, Lingren, T, McKnight, AJ, Kee, F, Jockel, K-H, McCarthy, M, Palmer, CNA, Vitart, V, Hayward, C, Simonsick, E, van Duijn, CM, Jin, Z-B, Feng, Q, Qu, J, Hishigaki, H, Lin, X, Marz, W, Gudnason, V, Tardif, J-C, Lettre, G, t Hart, LM, Elders, PJM, Damrauer, SM, Ramdas, Shweta, Kullo, IJ, Kumari, M, Kivimaki, M, van der Harst, P, Spector, TD, Loos, RJF, Province, MA, Parra, EJ, Cruz, M, Psaty, BM, Brandslund, I, Narita, A, Pramstaller, PP, Rotimi, CN, Christensen, K, Ripatti, S, Widen, E, Hakonarson, H, Grant, SFA, Kiemeney, LALM, de Graaf, J, Loefer, M, Takayama, J, Kronenberg, F, Gu, D, Erdmann, J, Schunkert, H, Franks, PW, Linneberg, A, Jukema, JW, Khera, A, Mannikko, M, Jarvelin, M-R, Martin, HC, Kutalik, Z, Francesco, C, Mook-Kanamori, DO, van Dijk, KW, Watkins, H, Strachan, DP, Grarup, N, Sever, P, Poulter, N, Chuang, L-M, Hunt, KA, Rotter, J, Dantoft, TM, Karpe, F, Neville, MJ, Timpson, NJ, Cheng, C-Y, Wong, T-Y, Khor, CC, Sabanayagam, C, Trivedi, B, Peters, A, Gieger, C, Hattersley, AT, Pedersen, NL, Magnusson, PKE, Boomsma, D, Willemsen, AHM, Cupples, L, van Meurs, JBJ, Ghanbari, M, Haessler, J, Gordon-Larsen, P, Huang, W, Kim, YJ, Tabara, Y, Wareham, NJ, Langenberg, C, Zeggini, E, Kuusisto, J, Laakso, M, Ingelsson, E, Giulianini, F, Abecasis, G, Chambers, JC, Kooner, JS, de Vries, PS, Morrison, AC, Hazelhurst, S, Ramsay, M, North, KE, Daviglus, M, Kraft, P, Bradford, Y, Martin, NG, Whitfeld, JB, Abbas, S, Saleheen, D, Walters, RG, Holmes, M, Black, C, Smith, BH, Baras, A, Justice, AE, Miller, JE, Buring, JE, Ridker, PM, Chasman, D, Kooperberg, C, Tamiya, G, Yamamoto, M, van Heel, DA, Trembath, RC, Wei, W-Q, Jarvik, GP, Zhu, Xiang, Campbell, A, Namjou, B, Hayes, MG, Ritchie, MD, Jousilahti, P, Salomaa, V, Hveem, K, Asvold, BO, Kubo, M, Kamatani, Y, Okada, Y, Lin, K, Murakami, Y, Kim, B-J, Thorsteinsdottir, U, Stefansson, K, Zhang, J, Chen, YE, Ho, Y-L, Lynch, JA, Rader, DJ, Tsao, PS, Millwood, IY, Chang, K-M, Cho, K, O'Donnell, CJ, Gaziano, JM, Wilson, PWF, Frayling, TM, Hirschhorn, JN, Kathiresan, S, Mohlke, KL, Sun, Y, Rasheed, A, Morris, AP, Boehnke, M, Brown, CD, Natarajan, P, Deloukas, P, Willer, CJ, Assimes, TL, Peloso, GM, Demirkan, A, Hindy, G, Faul, JD, Zhao, W, Weir, DR, Turman, C, Huang, H, Clarke, Shoa L., Graf, M, Choudhury, A, Sengupta, D, Mahajan, A, Brown, MR, Zhang, W, Yu, K, Schmidt, EM, Pandit, A, Gustafsson, S, Bhatti, Konain Fatima, Yin, X, Luan, J, Zhao, J-H, Matsuda, F, Jang, H-M, Yoon, K, Medina-Gomez, C, Pitsillides, A, Hottenga, JJ, Wood, AR, Vedantam, Sailaja, Ji, Y, Gao, Z, Haworth, S, Yousri, NA, Mitchell, RE, Chai, JF, Aadahl, M, Bjerregaard, AA, Yao, J, Manichaikul, A, Winkler, Thomas W., Hwu, C-M, Hung, Y-J, Warren, HR, Ramirez, J, Bork-Jensen, J, Karhus, LL, Goel, A, Sabater-Lleal, M, Noordam, R, Mauro, P

The power of genetic diversity in genome-wide association studies of lipids

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